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EVALUATING BLOOD TESTS FROM A TCM PERSPECTIVE

 

The following is a list of common serological tests. The General Laboratory Values are first listed. The “optimum values” are what is preferred. In the left hand column you will find the Western medical problem; in the right hand column you will find the common syndrome most often found in combination with the medical problem and the elevation or depression of the blood chemistry.

 

Key:     ^  &  > =          increased; more, heightened; intensified

<          =          decreased; less, diminished

 

BLOOD

 

RED BLOOD COUNT (RBC)

            The red blood cell is a carrier of oxygen through the hemoglobin it contains. The RBC value measures the actual oxygen carrying ability of the blood.

 

General Laboratory Values:              Male:                4.4-6.2 million cu.MM

                                                                        Female:            3.8-5.4 million cu.MM

 

Red Blood Cell Increased In:

B6 Anemia                                                       Sp, Kid Qi Xu

Emphysema (check HGB)                                Sp, Kid, Lu Zi Xu; Lu Yin Xu

Respiratory Distress (check total protein)          Kid Qi Xu; Lu Qi Xu

Adrenal Hyperfunction (check potassium)         Kid Damp Heat

Cystic Fibrosis                                      Sp Qi Xu; Liv Stagnation

                                                                        Damp Heat

 

Red Blood Cell Decreased in:

Iron Anemia (check HGB)                                Sp Qi Xu; Lu Qi Xu

Folic Acid Anemia (check MCV/MCH)           Sp Qi Xu

Hereditary Anemia                                            <Jing Qi; Sp Qi Xu

Liver Dysfunction (check SGPT)                       Li Stagnation; Li Heat

Renal Dysfunction (check creatinine)                 Kid Qi Xu

Free Radical Pathology                         <Wei Qi; Sp, Kid Qi Xu

 

General Picture of Toxic Metal Poisoning

Increased                                                       Decreased

Eosinophils, Bilirubin, BUN                               RBC, HCT, HGB, MCV, MCH

 

General Picture of Cadmium Poisoning (including toxic metal)

Increased                                                       Decreased

SGOT, SGPT, Calcium                                    Phosphorous

 

General Picture of Mercury Poisoning (including toxic metal)

Increased                                                       Decreased

SSGOT, SGPT                                                CO 2

 

General Picture of Arsenic Poisoning (including toxic metal)

Increased                                                         Decreased

Alkaline Phosphatase

 

RX: Toxic Metal Poisoning

 

Methionine, L-Cysteine, L-Glutathione – sulfur amino acids detoxify metals

Selenium/Vitamin E – anti-oxidant

Zinc - <zinc associated with toxic metal >

Calcium/Magnesium – prevents lead particularly from depositing in body (^EOS)

Vitamin C – heat in bld; (^EOS; ^Uric Acid)

Garlic – helps to bind and excrete toxic metals esp. lead

Milk Thistle Extract – hepatoprotective; (^EOS; ^BUN; ^Uric Acid)

Isatis Formula – w/ infx; toxic heat in liver; (^BUN; ^Uric Acid)

Fiber Combination – removes toxic metabolites more quickly; broom effect

Siberian Ginseng Combination – adaptogenic; reduces metal and radiation poisoning

 

NOTE: After detoxification is achieved use an adaptogen such as American Ginseng, Siberian Ginseng, or Siberian Ginseng Combination one month per year is an excellent prophylactic measure.

 

HEMATOCRIT (HTC)

            Hematocrit represents the packed cell volume of red blood cells. It is the percentage of the total volume occupied by packed red blood cells when a given volume of whole blood is centrifuged at a constant speed for a constant period of time. HCT is one of the most precise ways of measuring the degree of anemia. Hematocrit combined with serum iron and hemoglobin is a diagnostic tool for determining iron excess or deficiency.

 

General Laboratory Values:              Males:              39-54%

                                                                        Females:           35-48%

 

Hematocrit Increased In:

Dehydration                                                      Kid Yin Xu; Lu Yin Xu; Ht Bld Xu

Asthma                                                 Spleen Qi Xu; Kid Qi Xu; Lu Qi Xu

Emphysema                                                      Spleen Qi Xu; Kid Qi Xu; Lu Qi Xu; Lu Yin Xu

Respiratory Distress                                          Kid. Qi Xu; Lu Qi Xu

Adrenal Hyperfunction                          Kidney Damp Heat

Diarrhea                                                           Spleen Damp Heat; LI Damp Heat

 

Rx. Hematocrit Increased

 

Capilaris & Hoelen Formula                  – Damp Heat (diarrhea; adrenal^)

Hoelen 5 Formula                                 - Dampness (diarrhea; adrenal hyperfx)

 

Hematocrit Decreased In:

Parasites                                               LI Stagnation; Liver Stagnation, Sp Qi Xu

Adrenal Hypofunction               Kid Qi Xu

Anemias                                               Spleen Qi Xu; Lu Zi Xu; LI Xu; Liver Bld. Def.

Digestive Inflammation              Spleen Qi Xu; Damp Heat Spleen

Liver Dysfunction                                  Liver Stagnation; Live Heat

Renal Dysfunction                                 Kid Qi Xu

Rheumatoid Arthritis                             Spleen Qi Xu; Kid Qi Zu, <Wei Qi; Liv. Stag.

 

Rx. Hematocrit Decreased

 

Ginseng & Longan Formula                  - Qi/Blood Def (B 12 def; folic acid def; fe<)

Ginseng Nutritive Formula                     - Qi/Blood Def (B1 def; B12<; fe<)

Tang Kuei & Ginseng 8 Formula           - Qi/Bld Def (B-12<; adrenal<)

Minor Bupleurum Formula                    - Liv Stag.; St Phlegm; (Liv dysfx; parasites)

Bupleurum & Cinnamon Formula          - Liv Stag. w/Ht; (Liv dysfx; rheumatoid arthritis)

 

HEMOGLOBIN (HGB)

            Hemoglobin is the circulating iron containing pigment, which carries oxygen from the lungs to the tissues. It is a measurement of how earth feeds metal. Hemoglobin’s ability to transport oxygen depends upon pH and the presence of ferrous iron. Hemoglobin is the most abundant protein found within the red blood cell. Hemoglobin level measures the amount of intracellular iron. Hemoglobin is synthesized in most bodily tissues but the liver is the largest heme producing organ. (The muscles being fed by iron as well as glucose – liver). In the bone marrow heme is transformed into hemoglobin. It is also a measurement of how the metal manipulates the wood.

            It is important to note that infants have a higher hemoglobin level than adults. (growth/wood excess in infants). Hemoglobin is considered along with hematocrit, red blood cells, MCV and MCH in determining anemia. Ideally serum iron and ferritin will also be measured.

 

General Laboratory Values:              Males:              13.0 – 18.0 G/DL

                                                                        Females            11.5 – 16.0 G/DL

 

Hemoglobin Increased In:

Asthma                                                 Spleen Qi Xu; Kid Qi Xu; Lu Qi Xu

Emphysema                                                      Spleen Qi Xu; Kid Qi Xu; Lu Qi/Yin Xu

Adrenal Dysfunction                                         Kidney Damp Heat

Diarrhea/Dehydration                                        Spleen Damp Heat; LI Damp Heat

 

Serum Profile of Asthma

Increased                                           Decreased

HGB, HCT                                          Lymph

QBC, Eosinophils                                 Potassium

 

Rx: Asthma

Homeopathic Remedy                          - Arsenicum Album; Pulsatilla; Phosphorous

Antronex                                              - Liver Stagnation

Pancreatic Enzyme                                - Sp Qi Xu

Adrenal Extract                                    - Kid Qi Xu

Calcium/Magnesium                              - will alleviate wiry pulse

Minor Blue Dragon Formula                 - Phlegm/Damp; Lu Qi Zu; ^EOS

Pinellia X Formula                                - Phlegm/Damp Heat; sinus; ^LDH, ^EOS, <K

Pueraria Formula                                  - Wind Cold; GB congestion; ^EOS, ^WBC

 

Hemoglobin Decreased In:

Parasites                                               LI Stagnation; Li Stagnation; Sp Qi Xu

Adrenal Hypofunction               Kid Qi Xu

Anemias                                               <Wei Qi; Lu Qi Xu; Sp Qi Xu; Kid Xu; Jing Qi Xu

Digestive Inflammation              Sp Qi Xu; Sp Damp Heat

Liver Dysfunction                                  Li Stagnation; Li Heat; Li Heat Rising

Renal Dysfunction                                 Kid Qi Xu]

Rheumatoid Arthritis                             Spleen Qi Xu; Kid Qi Xu; <Wei Qi

 

Serum Profile of Iron Anemia

Increased                                           Decreased

B 12                                                     RBC, HCT, HGB, Iron

Globulin above 2.8                               MCV, MCH, MCHC

                                                            Bilirubin

 

Rx: Iron Anemia

 

Alfalfa Extract                           - TID two weeks; BID two weeks

Liver Extract                             - TID (<HCT, <HGB, <Fe, <Bilirubin)

HCL                                        - with meals – (<Fe)

Floradix                                    - TID (<HCT, <HGB)

Dong Quai Combination           - Blood Def; w/Sp Qi Xu)

Tang Kuei Four Formula           - Blood Def; anemia<aft. Mense; (<HCT, HGB, Fe, RBC)

 

Serum Profile of B12 Anemia

Increased                                           Decreased

HGB, MCV, MCH, Iron                      WBC, Cholesterol

Eosinophils                                           Potassium, B12, Albumin

 

Rx: B12 Anemia

 

Folic Acid/B12                         400 mcg/500 mcg TID – 2 weeks

                                                            400 mcg/500 mcg BID – 2 months

Liquid B Complex                                one dose BID – 2 months

]Thymus Extract                                   two tablets TID – 2 weeks

Tang Kuei & Ginseng Form.                 Sp & Liv Bld Def; fatigue (MCV^; MCH^, WBC<) following mense or illness

Ginseng & Longan Formula                  Sp Qi Xu; calmative; insomnia

Ginseng Nutritive Formula                     Geriatric anemia (^MCV; ^MCH; <WBC)

Floradix                                                Consider for vegetarians and Cold Sp/St

Dong Quai Combination                       Sp Qi Xu; thyroid imbalance

 

Serum Profile of Folic Acid Anemia

Increased                                           Decreased

MCV; MCH; Iron; LDH                      RBC; HGB; HCT; Folate, Uric Acid, Potassium

 

Rx: Folic Acid Anemia

 

Folic Acid/B12                         400 mcg/500 mcg TID – 2 weeks

                                                            400 mcg/500 mcg BID – 2 months

Liquid B Complex                                one dose BID – 2 months

Alfalfa Extract                                       dose TID

Ginseng & Astragalus Formula  Sp Qi Xu; (Folate<, RBC<, MCV>)

Tang Kuei & Peony Formula                Bld Xu; Kid Qi Xu; (MCV>, Folate<; HGB<; HTC<)

 

Notations

 

            It is difficult to differentiate between folic acid anemia and B-12 anemia. One generalization: if the patient is suffering with a looser stool, supplement first with folic acid. If the patient has leanings more toward constipation, use B-12 first. With both anemias the Qi of the Stomach is diminished. Herbal Spleen Qi enhancing formulas such as Ginseng and Astragalus as well as/or HCL should be considered.

B-12 and Folic Acid should be considered when dealing with inflamed nerve tissue or degeneration (myalgias), blood sugar disorders, vegetarians and pregnant women. (Pregnancy/neural tube defect). Iron anemia could be the outcome of a history of excessive aspirin use. If sclera of the eyes are blue, need for iron.

 

MEAN CORPUSCULAR VOLUME (MCV)

            MCV indicates the volume in cubic microns occupied by an average single red blood cell. MCV increases or decreases with an increase or decrease in MCH is a finding for folic acid/B-12 deficiency (increase) or iron, copper or B-6 (decrease).

 

General Laboratory Values:  80 – 100 cuMM

 

MCV

Increased                                           Decreased

Folic acid/B-12 anemia             Parasites (check eosinophils)

Hereditary anemia                                 Iron anemia (check HGB)

                                                            Hypochlorhydria (check food allergies)

                                                            B-6 anemia; Vit. C anemia

                                                            Rheumatoid arthritis; Lead poisoning

 

MEAN CORPUSCULAR HEMOGLOBIN (MCH)

            MCH indicates the weight of hemoglobin in a single red blood cell. When MCH >s or <s with an > or < in MCV it is an indicator for folic acid and/or B-12 deficiency. A < in MCH with a < in MCV will point to an iron, B-6 or copper deficiency.

 

General Laboratory Values:              27 – 33 micro micrograms

 

MCH

Increased                                           Decreased

B-12/Folic Acid anemia                        Parasites

Hereditary anemia                                 Iron anemia, Copper deficiency

                                                            Rheumatoid Arthritis (check Alk Phos)

                                                            Toxic metal poisoning – lead, etc.

 

MEAN CORPUSCULAR HEMOGLOBIN CONCENTRATE

            Indicates the hemoglobin concentration per 100ml of packed red blood cells.

 

General Laboratory values:                          31 – 36%

 

PLATELETS

            Platelets, or thrombocytes, are tiny bits of cytoplasm, much smaller than the red blood cells but lacking a nucleus. They are round or biconcave disks and are normally about 30 to 40 times more numerous than the white blood cells. They are produced as broken fragments of the cytoplasm of the giant cells of the bone marrow – the megakaryocytes. The platelets’ primary function is to stop bleeding, with the help of certain clotting proteins in the plasma. When tissue is damaged, the platelets aggregate in clumps to obstruct blood flow through the smallest vessels, the capillaries. In the larger vessels, the clumps of platelets form a site around which a blood clot forms, aided by a clot-promoting factor freed by the platelets as they break down. In short, platelets are responsible in the blood clotting mechanism.

 

General Laboratory Values:                              150,00 – 450,00 CuMM

 

Platelets

Increased                                           Decreased

Anemia                                     Anemia

Rheumatoid Arthritis                             Liver Dysfunction; Lupus

 

QI

 

WHITE BLOOD CELLS (TOTAL WHITE BLOOD CELL COUNT)

            White Blood Cells are divided into two groups: 1) Granulocytes: neutrophils, eosinophils and basophils, 2) Nongranulocytes: lymphocytes and monocytes.

 

General Laboratory Values:                              4 – 11 Thous./cu.mm.

 

WBC

Increased                                                       Decreased

Measles, Mumps (onset)                                   Measles, Mumps (Late)

Mono (2nd/3rd wk)                                            Mono (1st wk/chronic)

Parasites                                                           Parasites

Adrenal Dysfunction                                         Adrenal Dysfunction

Infection (abscess)                                            Chronic Infection (viral/bacterial)

Flu w/additional infx.                                         Flu (onset)

Asthma                                                 B-12, B-6, Folic Acid Anemia

                                                                        Lupus Erythematosis (LDH^; SED^)

                                                                        Monos^; Cholest^; Albumin<; HCT/HGB<;

                                                                        Lymphs<; Platelets<

 

RX: Elevated WBC’s

Week #1                      Yin Qiao – one dose QID – first 48 hours

                                    Echinacea Combination – one dose TID/QID

                                    Vitamin C mineral ascorbate – 500-1000 MG QID

                                    Thymus Extract – 2 tablets TID

                                    Proteolytic Enzymes – dose TID betw. Meals

                                    Consider stomach protective measurement

 

Week #2                      Isatis Formula – dose TID

                                    Zinc Picolinate – 15 mg. BID

                                    Consider short course of pancreatic enzyme for Spleen Deficiency

 

Week #3                      Minor Bupleurum Formula – dose TID

                                    Thymus Extract – dose TID

 

NEUTROPHILS

            Neutrophils are predominantly involved with phagocytosis. Neutrophil count is a way of determining the strength of the immune system’s ability to fight infection.

 

General Laboratory Values:              45 – 75 percent of total WBC’s

 

NEUTROPHILS

Increased                                                       Decreased

Infection                                                           Infection

Adrenal Dysfunction; Gout                                Bone Marrow Depression

Pregnancy – Last Trimester                               Iron, B-12, Folic Acid

 

BANDS OR NON-SEGMENTED NEUTROPHILS

            Bands are the youngest form of neutrophils typically found in the peripheral blood. They increase during acute infection with or without an increase in the total WBC. BAND measurement is useful in determining an infectious process.

 

General Laboratory Values:                         0 – 10% of total WBC’s

 

BANDS

Increased                                                       Decreased

Acute Infection                                     Not considered a significant finding

 

LYMPHOCYTES

            Lymphocytes help to destroy toxic metabolites of protein metabolism. They originate from lymphoblasts in the spleen, lymph, glands, tonsils, bone marrow and thymus. They help to determine the stage of infection: acute; recovery; chronic. Generally when lymphs are high there is some systemic toxicity; when lymphs are low there is often chronic viral infection.

 

General Laboratory Values:                         18 – 46 percent

 

LYMPHOCYTES

Increased                                                       Decreased

Infection; Flu                                                    Infection; Flu

Parasites                                                           Lupus

Anterior Pituitary Hypofunction             Late Pregnancy

Adrenal Dysfunction                                         Adrenal Dysfunction

Hyperthyroidism                                               Immune Deficiency

 

RX: Acutely Increased Lymphocytes

Day #1:                        Aconite 200x – one dose

                                    Yin Qiao – one dose QID

                                    Curing Formula – one dose TID

 

Days #2 – 5:                 Echinacea Combination – one dose QID

                                    Consider additional Echinacea

                                    Vitamin C – 1,000 MG QID

                                    Wobenzyme – one/two with meal

                                    Consider proteolytic enzymes between meals

 

Days #6 – 10               Isatis Formula – one dose QID

                                    Acidophilus/Bifidus – one dose BID

                                    Wobenzyme – one/two with meal

                                    Zymex II – 3 caps two times daily between meals

                                    Jade Screen Formula – dose BID

 

MONOCYTES

            The monocyte is a young macrophage. The cells that line sinusoids in spleen, liver and lymph notes derive from the same monocyte-macrophage pool. Normal macrophages have enzyme systems capable of synthesizing and of degrading sphingolipids, compounds important in biologic membranes and especially prominent in the nervous system. Monocytes are of primary importance in diagnosing mononucleosis. At the onset of illness the WBC may be low but by the end of the first week the count will usually be between 10,000 - 30,000mm. There is an  increase in lymphocytes as well as monocytes which will often be over 15%.

 

General Laboratory Values:                                     0 - 10%

 

MONOCYTES

Increased                                           Decreased

Parasites                                                           Not Significant

Hepatitis (SGPT)

Benign Prostate Hypertrophy (Creatinine)

Acute Infection; Mumps

 

RX: ELEVATED MONOCYTES

            Addressing liver stagnation is most important. Simultaneously consider blood cleansers, anti-virals and liver regulators.

 

EXAMPLE

Day #1:                        Echinacea Combination - 2 droppers 5x daily

                                    Vitamin C - 1,000 mg. - 5x daily

                                    Appropriate Homeopathic - 4x daily

                                    (Oscillococinnum)

Days #2, 3, 4:               Echinacea Combination - 2 droppers 3x daily

                                    Isatis Formula (with stronger spleen) - 2 droppers 3x daily

                                    Adrenal Extract and Vitamin C - QID

Days #5,6,7:                 Isatis Formula - 2 droppers 2x daily

                                    Minor Bupleurum Formula - 2 droppers 3x daily

                                    Merc. Sol, Merc. Viv, or Merc. Dulc. - dose 3x daily

 

EOSINOPHILS (EOS)

            Eosinophils are the mediators in acute inflammation and increase with allergies, some skin disease, after radiation exposure and parasites. EOS are involved with the detoxification and removal of excess proteins. W/ elevation food sensitivities are important to consider. Elevated eosinophils are decreased with adrenal support. It is important when regulating EOS that urinary and saliva pH is maintained between 6.0-6.5.

 

General Laboratory Values:             0-6%

 

EOSINOPHILS

Increased                                                    Decreased

Allergies (IgE)                                                  not significant

Asthma (IgE/HGB)

Rheumatoid Arthritis (Alk. Phos.)

Hayfever; Dermatological Disorders

Parasites (IgE/<Fe/MCH/MCV/HGB/HCT)

Hyperthyroidism (T3 Uptake)

Adrenal Cortical Hypofunction (K)

Anterior Pituitary Hypofunction (TSH)

 

RX: ELEVATED EOSINOPHILS

Week #1:         Rule out need for HCL

                        Echinacea Extract - 2 droppers TID

                        Pancreatic Enzymes - dose w/ meals

                        Zymex - (for children) - dose BID

                        Thymus Extract - dose TID

Week #2:         Pancreatic Enzymes

                        Adrenal Extract - dose TID

                        Vitamin C - dose TID

Symptom specific formula: Minor Bupleurum; Minor Blue Dragon; Du Huo and Loranthus; Pueraria comb.; or Milk Thistle Extract

Calcium/Magnesium - dose BID

Week #3:         Syndrome specific herbal formula

                        Thymus/Adrenal as needed

                        Vitamin C - BID

                        Zinc - BID

                        B-12 - BID

 

BASOPHILS (BASO)

            Basophils contain enzymes called lysosomes. Lysosomes activate the release of histamine and hyaluronic acid. Basophils release heparin essential to fighting inflammation and preventing clotting of the blood in inflamed tissue. Hyalouronic acid is an interstitial adhesive/protective factor whose production is associated with cortisol output.

 

General Laboratory Values:                         0 -2%

 

BASOPHILS

Increased                                           Decreased

Parasites (EOS)                                                not significant

Chickenpox (WBC)

Flu; Inflammation

Hypothyroidism (T3/T4)

Chronic Hemolytic Anemia (RBC/HGB)

 

FIRE: HEART/PERICARDIUM/SMALL INTESTINE

 

SEDIMENTATION RATE

The Sedimentation Rate helps to determine inflammation and/or destruction within a disease process. It helps in following the course of an established condition and also signals the onset of inflammation. Fibrogen increases the Sed. Rate, while an increase in albumin decreases the Sed. Rate. The liver is the seat of albumin synthesis. A damaged liver, therefore, can contribute to low albumin with a corresponding increased Sed. Rate.

 

General Laboratory Values:                         Male - 0 - 15 MM/HR

                                                                        Female - 0-20 MM/HR

 

SEDIMENTATION RATE

Increased                                           Decreased

Inflammation                                                     Not significant

 

THYROID

Thyroid Hormones

            Control of oxygen consumption is the most conspicuous biologic effect of the thyroid hormones, a physiologic variable measured in simplest fashion by the basal metabolic rate. Thyroid hormones also influence carbohydrate and protein metabolism, and the mobilization of electrolytes, and the conversion of carotene to vitamin A. (wood/fire). Although the mechanism is not fully apparent, thyroid hormones are essential for development of the CNS and the thyroid deficient infant suffers irreversible mental damage. The thyroid deficient adult may have slowed deep tendon reflexes.

            Thyroid hormones affect synthesis and metabolism of fats. Abnormalities within the endocrine system may be reflected in altered lipid levels. In hyperthyroidism, degradation and excretion increase more than synthesis, resulting in low levels of cholesterol and triglycerides. Hypothyroidism slows catabolism more than it affects synthesis, and hypercholesterolemia and hypertriglyceridemia. Hypothyroidism secondary to pituitary failure, however does not cause lipids to rise. In an obviously hyypothyroid patient, a normal serum cholesterol level should direct attention to the pituitary. (Is the problem wood or water). Cholesterol levels will often drop within 3 weeks after thyroid medication.

 

            The thyroid gland synthesizes its hormones from iodine and the essential amino acid tyrosine. Most of the body's iodine enters through the alimentary tract as iodide, but under certain circumstances, the lungs and skin may be portals of entry. Of the iodine that enters the body, approximately one third enters the thyroid gland and two thirds leaves the body in urine.

 

Enzymes oxidize iodide to organic iodine, which is incorporated into monoiodotyrosine and diiodotyrosine. These one and two iodine containing compounds are building blocks for the active thyroid hormones T4 which has four iodine molecules, and triiodothyronine T3, which has three.

 

T-3 UPTAKE

Useful to dx. Hyperthyroidism.

 

General Laboratory Values:             .8 - 1.2

 

T-3

Increased                                           Decreased

Hyperthyroidism                                               Hypothyroidism; Pregnancy

Protein Malnutrition                                          Estrogens/Anti-Ovulatory Drugs

Renal Dysfunction                                             Triiodothyronine Rx. for Hypothyroidism

                                                                        Propylthioouracil Rx. for Hyperthyroidism

 

T-4 THYROXINE

            T-4 is a product of the thyroid follicular cell. It influences the entire body's metabolism. In primary hypothyroidism T-4 levels are usually low. In many cases of sub-clinical hypothyroidism (chk. Daily temperature), T-4 levels may be low normal.

 

General Laboratory Values:             4.5 - 12 mcg/100m.

 

T-4

Increased                                           Decreased

Hyperthyroidism                                               Hypothyroidism, Renal Dysfunction

Liver Cirrhosis                                      Diabetes; Anterior Pituitary Dysfunction

Pregnancy                                                        Protein Malnutrition

 

THYROID STIMULATING HORMONE (TSH)

            TSH is secreted from the pituitary gland. It regulates the uptake of iodine as well as the synthesis and secretion of the thyroid hormones. TSH is influenced by hypothalamic stimulation as well as T4 concentration.

 

General Laboratory Values:             .4 - 6 mcIU/ml

 

TSH

Increased                                           Decreased

Hypothyroidism                                                Hyperthyroidism

Liver Cirrhosis                                      Anterior Pituitary Hypofunction

 

Hyperthyroidism

Increased                                           Decreased

T4, T3 Uptake; Glucose; BUN             Basophils; Albumin; Calcium

Alkaline Phos; Eosinophils                                Total Protein; HCT; HGB; Iron

                                                                        Magnesium; Cholesterol; Triglycerides

 

Hypothyroidism

Increased                                           Decreased

LDH, Calcium, Magnesium                               T3 Uptake; T4; HCT; HGB; Iron

Basophils; Cholesterol; Triglycerides                 Sodium

 

SYMPTOMATOLOGY

Hypothyroidism                                    Hyperthyroidism

>Cholesterol, Triglycerides                         <cholesterol, triglycerides

>Serum Carotene (yellow skin)             >skin temp, pulse rat, pulse pressure

>Muscle Enzymes: CPK, AST, LDH                >Alkaline Phosphatase

>Prolactin                                                         Altered glucose/insulin relationship

Anemia; HGB @ 10g/dl                                   >Proportion of lymphs in differential WBC

Capillary fragility                                               >Urinary calcium excretion

Spinal fluid protein

 

Pituitary/Hypothalmus

            The thyroid produces hormones upon stimulation by the pituitary hormone variously called thyrotropin or thyroid stimulating hormone (TSH). Pituitary production of TSH (Kidney energy) follows stimulation by a hypothalamic protein called thyrotropin releasing hormone (TRH), which responds to activity levels of T3 and T4 in the blood passing through the hypothalamus. When hormone levels are low TRH provokes TSH secretion, which then accelerates all aspects of thyroidal iodine metabolism and hormone production.

 

EARTH: STOMACH/SPLEEN

 

GLUCOSE

            This test is a useful indicator of glucose metabolism disorders.

            Glucose represents the synthesis of carbohydrates and is the form in which carbohydrate is supplied to the cell from body fluids. In other words, glucose is the essence (yin) of carbohydrate metabolism. Insulin, of particular importance in the transport of glucose into the fat cell, lowers serum glucose while adrenal and pituitary hormones tend to elevate it through their effects on the liver. The thyroid gland, on the other hand, by helping with the selective activity of the intestinal tract for sugar, increases blood sugar if it is overactive and decreases blood sugar if it is under-active.

            Since brain cells cannot derive energy from anaerobic metabolism of glucose, they are most vulnerable to hypoglycemia (enter – brain fog”)

 

General Laboratory Values:              65-115 MG/DL

 

Glucose Increased

Diabetes                                                           Damp Heat in Spleen; Liv. Stag.

Acute/Chronic Pancreatitis                                Damp Heat in Spleen

Digestive Inflammation                          Damp Heat in Spleen

Digestive Inflammation                          Damp heat in Spleen

Hyperthyroidism                                               Damp Heat in Spleen; Liv. Stag.

Pregnancy                                                        Damp Heat in Spleen

Adrenal Cortical Hyperfunction             Damp Heat in Kidney

Chronic Renal Dysfunction                                Damp Heat in Kidney

Cardiac Dysfunction                                         Damp Heat in Heart

 

Glucose Decreased

Hypothyroidism                                                Spleen Qi Xu

Malnutrition                                                      Spleen Qi Xu

Pregnancy                                                        Spleen Qi Xu

Hypochlorhydria                                               Spleen Qi Xu

Liver Dysfunction                                              Spleen Qi Xu; Wind Attacking Earth

Hypoglycemia                                                   Spleen Qi Xu; Kidney Qi Xu

Anterior Pituitary Dysfunction                Kidney Qi Xu

Adrenal Cortical Hypofunction              Kidney Qi Xu

 

Diabetic Blood Profile

Increased                                                    Decreased

Glucose; Basophiles; Creatinine                                    Calcium; Insulin; Lymphocytes; T-cells

GGTP, Triglycerides; Cholesterol                                  Blood pH; Phosphorous; Chloride

BUN; Uric Acid; Alk. Phos & LDH – normal-^            Albumin & Magnesium – normal to <

 

It is interesting to note that with diabetes or pre-diabetic condition, the serum triglycerides will often be higher than the serum cholesterol. In Oriental Medicine this would relate to the predominant problem being Damp Heat in the Spleen as opposed to “pure” Liver Stagnation.

 

RX: HYPERGLYCEMIA (HERBAL)

Astragalus & Ganoderma Formula – Deficiency of Qi and Yin

Anem-Phello & Rhemannia Formula – Heat w/ Yin Deficiency

Bitter Herb Combination – Liv Stag.; Phlegm in Stomach/Sp.

Bupleurum/Dragon Bone Formula – Diabetes w/ hypertension

Dandelion Extract – Liver Stag.; ^Cholesterol/Trigs.

Goldenseal Extract – Heat in St.; Dampness; infx.

Echinacea Combination – if associated with infection

Garlic – Hyperglycemia w/atherosclerosis

 

RX: HYPERGLYCEMIA (NUTRITIONAL)

Chromium – 100 mcg. BID – Stabilizes blood sugar

L-glutamine – 500 mg. BID between meals or beg. meal; sustains blood sugar

Niacin/Niacinamide – 100 mg. 2X daily – every other week 3 months

Lipotropics (Choline, Methionine, Inositol) – 350 mg. BID – digest fats

Zinc (taste test) – 15 mg. BID; slow healing; check nails; fungal infx.

Vit. A (emulsion or cap) – 15,000 IU – diabetics have difficulty converting beta-carotene to Vit. A

Vit. C – Mineral ascorbate – 1,000 mg. TID

Vit. E – Caution with hypertensive diabetic – 200 IU BID – TID

 

TEST WHICH CAN BE DONE IN THE CLINIC

            Those who have an onset of diabetes with adulthood (type II diabetics) are not able to perceive sweet tastes easily. The taste buds must be very stimulated with a large amount of concentrated sweet for the taste to be perceive. It’s almost as if the Spleen has lost some of its intelligence, discerning power or Qi.

            This patients’ inability to perceive sweet tastes makes it very difficult for them to lose weight. WHY? They do not recognize sweet foods as such, and will often consume large amounts of sugary type foods. This test will often detect an impaired ability to taste sweets.

 

STEP #1:         Make sure the patient has not consumed caffeinated stimulants within the last three hours.

STEP #2:         Label seven glasses as: 1: No sugar; 2: Ό tsp. sugar; 3: ½ tsp. sugar; 4: 1 tsp. sugar, 5: 1 ½ tsp. sugar; 6: 2 tsp. sugar; 7: 3 tsp. sugar. Place these amounts of sugar in eight ounces of water.

STEP #3:         Have the patient sip with a straw from each glass. After each taste have them rinse their mouth with water. Most people without a sugar disorder will be able to perceive a sweet taste with only one teaspoon or less of sugar in the eight ounces of water. Most individuals with a sugar disorder will need 2 to 3 teaspoons of sugar present in the eight ounces to perceive sweetness.

 

THE HYPOGLYCEMIC BLOOD PROFILE

Increased                                           Decreased

Growth Hormone^                                           Glucose <

Insulin^                                                 LDH – normal to <

            A hypoglycemic may display any or all of the following symptoms: fatigue, dizziness, headache, irritability, depression, anxiety, tightness in the chest, sweet cravings, confusion, night sweats, weakness in the legs, nervous habits, insomnia and an assortment of pains. These symptoms relate to various syndromes, the most obvious being Spleen Qi Xu, Kid. Qi Xu and Liver Stag.

 

NOTATIONS

            A low normal glucose combined with a low normal LDH is reason to suspect hypoglycemia. In Oriental Medicine this would be associated with Spleen Qi Xu. Hypochlorhydria (St. Def.) and biliary stasis (Liver Stagnation) are prominent syndromes in most cases of hypoglycemia. Low blood pressure (Kid. Qi Xu) is also common amongst hypoglycemics.

            With blood sugar problems, a craving for sweets is common. Bile salts for a short period of time – 2 weeks, along with chromium, is an effective way to diminish this sweet craving. Ginseng & Astragalus and/or Ginseng & Atractylodes Formulas will enhance digestion and help to take the extreme dip out of the blood sugar curve. Homeopathics: Pulsatilla; Arg. Nit.

            Headaches associated with chronic low glucose: Ginseng & Astragalus Formula

            Hypoglycemia prior to menstruation is often due to a poor diet of excess sugar and fats. Harmonizing the liver/gallbladder with Bupleurum and Tang Kuei Formula (for the more Blood Def.) of Bupleurum and Paeonia Formula (for the more Liver Stag. wiry pulse) will assist in controlling the blood sugar before menses.

A flat glucose curve is common with learning disabilities and “personality disorders” or disturbed Shen. Heavy metals may also be the culprit here.

            Food allergies, especially gluten and milk, may often cause blood sugar fluctuations.

            If LDH and glucose are low and such symptoms as hypochlorhydria, (Sp. Qi Xu) hypotension and adrenal fatigue, (Kid. Qi Xu); and acidic urine and saliva (Stagnation) one must rule our food allergies. Avoidance of allergens, simple sugars and over-cooked fats is a must.

 

RX: HYPOGLYCEMIA (HERBAL)

            Ginseng & Astragalus Formula – Sp. Qi Xu; prolapse; taken betw. Meals will help to control blood sugar; taken w/ meals assists digestion.

            Saussurea & Cardamon Formula – Sp. Qi Xu; Damp; St. Stagnation; gas; w/meals to resolve digestive symptoms

            Ginger Extract – Cold; Stagnant St.; w/ meals for digestion; between meals for nausea, morning sickness

            Echinacea Extract – low grade infx. (5 days – 2x each month – 3 months)

            Licorice Extract may be added to Ginseng and Astragalus Formula. By itself effective as a Kid. Qi tonic for one week at a time. Administer at 11 AM and 3 PM. (do not use with hypertensives or individuals with sodium retention. Used historically in the treatment of Addison’s Dx (exaggerated Kid. Qi Xu). Licorice Extract enhances endogenous activity of mineralocorticoids via inhibition of degradation by the liver. Glycyrrhizin suppresses 5-beta-reductase, the main enzyme responsible for inactivating cortisol, aldosterone and progesterone. Glycyrrhiza also has significant anti-inflammatory and anti-allergic activity. Glycyrrhetinic acid was the first drug shown to treat peptic ulcers. Glycyrrhetinic acid also effective in speeding the healing of oral and genital herpes.

 

RX: HYPOGLYCEMIA (NUTRITIONAL)

Chromium

Bile Salts

Adrenal Extract

Liquid B Complex p 50 mg. 2x daily – imperative in carbohydrate metabolism. Augments Spleen Qi. Will create heat and is therefore not as effective in diabetes as in hypoglycemia.

B-12 – 500 mcg. As needed (may be given IM – 1 cc. Every 5 days for 4 doses. Will assist in bowel absorption of nutrients. Enhances communication or feeding from the earth to metal. Assists in resolution of diarrhea/constipation associated with food allergies/hypoglycemic symptoms.

Note: a useful injection: B complex (1 cc) plus pyridoxine (1/2 cc) once per week for one month has shown to be very effective in the beginning stages of treatment for hypoglycemia. This is a relatively mild treatment and can be combined with any of the herbal formulas. ACE injections in small amounts will also assist in initial stages of tx.

Pantothenic Acid – 350 mg. BID/TID – magnesium is important in sugar metabolism.

Lipotrophics (Choline, Methionine, Inositol) – Liv. Stag.; ^lipids

Fiber Combination (Guar Gum, Psyllium, etc.) – LI Stag.; may create a problem w/ Sp Qi Xu. Begin with small amounts.

 

METAL: LUNG/LARGE INTESTINE

 

CARBON DIOXIDE (CO2)

            In the combustion of food, oxygen is used and carbon dioxide is given off. The rate of oxygen consumption indicates the energy expenditure of an organism, or its metabolic rate. The metabolic rate of any given animal at any given time is highly variable and is influenced by many diverse factors, including amount of muscular activity; quality of diet; presence or absence of digestion, lactation or pregnancy; time of day or year; period of the menstrual cycle and emotional state. Although most CO@ is lost through the lungs, some is converted to bicarbonate. This bicarbonate is part of the alkaline reserve available for neutralization of acids. Arterial blood has a lower total CO2 than venous blood.

 

General Laboratory Values:                         22-32 mEq/L

 

CO2

Increased                                                    Decreased

Fever; Respiratory Distress/Alkalosis                            Dehydration; Acidosis

Adrenal Hyperfunction                                      Renal Dysfunction

 

TOTAL IRON

            Iron is largely absorbed across the mucosa of the duodenum and proximal jejunum. Gastric juice plays an important but not thoroughly understood role in promoting absorption. The low pH of gastric juice makes iron more available from iron-rich foods.

 

General Laboratory Values:                                          40 – 170 mcg/mL

 

IRON

Increased                                                    Decreased

Pernicious Anemia/B-12                                               Iron Anemia; Parasitic Infection

Liver/Kidney Dysfunction                                              Liver/Kidney Dysfunction; Gastrointestinal Dx. (peptic ulcer; diverticulitis)

 

CALCIUM

            Calcium is absorbed from the upper part of the small intestine. Absorption depends upon the relative acidity of the intestinal contents and the amount of phosphate present. Calcium absorption is influenced by parathyroid hormone, calcitonin and Vitamin D.

 

General Laboratory Values:                          8.5 – 10.5 mg/dl

 

Calcium

Increased                                                    Decreased

Hyperparathyroidism                                                    Hypoparathyroidism]

Ovarian Hyperfunction                                      Ovarian Hypofunction

Epilepsy                                                                       Osteoporosis; Acidosis; Hypochlorydria

 

PHOSPHOROUS

            Phosphorous plays an important role in the hemostasis of calcium and in reactions involving carbohydrates, lipids, and proteins. The chemical energy of the body is stored in “high energy phosphate: compounds. Calcium and phosphorous dynamics are largely regulated by the effects of parathyroid hormone on bone and on urinary excretion and the effects of vitamin D metabolites on intestinal absorption and on bone. Parathyroid hormone causes increased resorption of both calcium and phosphorous from bone; it suppresses urinary calcium, causing serum calcium levels to rise and serum phosphate levels to fall. Vitamin D stimulates absorption of calcium and phosphorous from intestinal contents, and accelerates the turnover of both minerals in the bone.

 

General Laboratory Values:                          2.5 – 4.5 mg/dl

 

PHOSPHOROUS

Increased                                                    Decreased

Renal/Liver Dysfx.                                                        Digestive Dysfx; <HCL

Ovarian Hyperfunction                                      Ovarian Hypofunction

Fractures; Increased Vit. D levels                                  Diabetes; Decreased Vit. D. levels

 

WATER: KIDNEY/BLADDER

 

SODIUM

            Sodium levels alone are of limited diagnostic use. It is important to compare the relative measurement of sodium vs. potassium. Excessive sodium levels implies heat in the kidney. Low levels of serum sodium imply Kidney Qi Deficiency.

 

General Laboratory Values:                         135 – 147 mEq/L

 

SODIUM

Increased                                                    Decreased

Adrenal Cortical Hyperfunction                         Adrenal Cortical Hypofunction

Congestive Heart Failure                                               Diabetes; Diarrhea

Diabetes; Water softeners                                             Excessive perspiration – following exercise

 

POTASSIUM

            Potassium levels can indicate in which general direction the body’s pH is going. Increased levels of potassium are indicative of acidosis while decreased levels are indicative of alkalosis. With chronic potassium elevation one has to consider immunodepression and/or inflammation.

 

General Laboratory Values:             3.5 – 5.3 mEq. per liter

 

POTASSIUM

Increased                                                    Decreased

Adrenal Hypofunction                                       Adrenal Hyperfunction

Asthma, Emphysema                                                    Vomiting; Diuretics; Diarrhea]

Renal Dysfunction                                                         Hypertension

 

CHLORIDES

            Sodium, potassium and chloride ions surround the cell plasma membrane. Comparing the measurements of these three ions one can get general information on the basic functioning of the kidney and the relationship of the water and the earth elements. Generally, elevated chlorides will represent Heat and decreased chlorides will represent Deficiency within the water elements.

 

General Laboratory Values:             96 – 109 mEq/L

 

CHLORIDES

Increased                                                    Decreased

CO2 deficiency                                                            CO2 excess

Adrenal Hyperfunction                                      Adrenal Hypofunction

Hyperaparathyroidism                                                   Respiratory distress

Dehydration                                                                  Diabetes

Salicylate toxicity                                                          Renal Dysfunction

 

BLOOD UREA NITROGEN (BUN)

            Urea is formed almost entirely by the liver from protein metabolism in the tissues. The rate of urea production is accelerated by a diet high in animal proteins and chronic tissue damage. It is believed that more than 50% of the kidney must be destroyed before serum urea levels are significantly elevated. Elevated BUN with normal creatinine usually signals a non-renal cause for uremia.

 

General Laboratory Values:                         7 – 25 mg/dl

 

BUN

Increased                                                    Decreased

Renal Dysfx; Gout; Heart Failure                                   Celiac Sprue; Advanced Acidosis

Liv/Biliary Dysfx; Rheum. Arthritis

 

CREATININE

            Creatinine clearance is a good measurement of glomerular function. It measures the rate of excretion by the kidneys of metabolically produced creatinine. Blood Creatinine rises when renal function declines. With severe renal impairment, urea levels continue to climb, but creatinine values plateau.

 

General Laboratory Values:                          .6 – 1.5 mg/dl

 

CREATININE

Increased                                                    Decreased

Reduced blood flow to kidney                          not significant

Urethral obstruction/stones

Shock, Blood Loss, Dehydration, Burns

Muscle trauma; Flu; Late pregnancy

 

URIC ACID

            Uric Acid is the chief end product of purine metabolism. Purines are constituents of nucleic acids. Most uric acid is synthesized in the liver, in a reaction requiring the enzyme xanthine oxidase. Uric acid travels through the blood to the kidneys, where filtration, absorption and secretion will affect uric acid excretion. Organ meats, legumes and yeast are especially high in purines.

            Uremia can be described as symptoms and physical abnormalities that result from the kidneys’ failure to remove nitrogenous waste products normally excreted in the urine. The toxic effects of uremia affect virtually all human organs. The most common symptoms are high blood pressure, swelling (edema) of the ankles, nausea, vomiting and weight loss. Anemia is almost always present because high blood levels of urea, one of the nitrogenous substances, shortens the life span of red blood cells. Other symptoms may include irritation of the heart sac (pericarditis), bleeding, muscle twitches and itching (pruritus). In the later stages, uremia causes agitation alternating with stupor, convulsions, coma, and ultimately death. Analysis of blood chemistries show elevated levels of urea, creatinine, uric acid, phosphorus and hydrogen ion.

 

General Laboratory Values: Males:     3.0 – 9.0 mg/dl

                                                            Females: 2.2 – 7.7 mg/dl

 

URIC ACID

Increased                     &